ﺑﺎﺯﮔﺸﺖ ﺑﻪ ﺻﻔﺤﻪ ﻗﺒﻠﯽ
خرید پکیج
تعداد آیتم قابل مشاهده باقیمانده : 3 مورد

Summary of outcomes for pregnancy in individuals with mitral stenosis

Summary of outcomes for pregnancy in individuals with mitral stenosis
Stage of MS* Source of data Total number of pregnancies Maternal outcomes Fetal outcomes
Death Pulmonary edema or heart failure New/recurrent arrhythmias Stillbirth Neonatal death Preterm birth
Progressive
(MVA >1.5 cm2)		 3 studies[1-3] 118 0% 18% 3% 1% 0% 8%
Severe
(MVA 1.0 to 1.5 cm2)		 Systematic review of 8 studies[4] 287 1% (95% CI 0-2%) 18% (95% CI 2-33%) 5% (95% CI 1-9%) 2% (95% CI 1-4%) 0% 10% (95% CI 2-17%)
Very severe
(MVA <1.0 cm2)		 174 3% (95% CI 0-6%) 37% (95% CI 23-51%) 16% (95% CI 1-25%) 4% (95% CI 1-7%) 2% (95% CI 0-4%) 18% (95% CI 7-29%)

MS: mitral stenosis; MVA: mitral valve area.

* The stages of MS in this table were revised to reflect those in the 2020 American College of Cardiology/American Heart Association (ACC/AHA) guidelines for valvular heart disease.[5] The names of these stages differ from those originally used in the cited studies.

¶ These 3 studies were also included in the systematic review.
References:
  1. Hameed A, Karaalp IS, Tummala PP, et al. The effect of valvular heart disease on maternal and fetal outcome of pregnancy. J Am Coll Cardiol 2001; 37:893.
  2. Silversides CK, Colman JM, Sermer M, Siu SC. Cardiac risk in pregnant women with rheumatic mitral stenosis. Am J Cardiol 2003; 91:1382.
  3. van Hagen IM, Thorne SA, Taha N, et al. Pregnancy outcomes in women with rheumatic mitral valve disease: Results from the registry of pregnancy and cardiac disease. Circulation 2018; 137:806.
  4. Ducas RA, Javier DA, D'Souza R, et al. Pregnancy outcomes in women with significant valve disease: A systematic review and meta-analysis. Heart 2020; 106:512.
  5. Otto CM, Nishimura RA, Bonow RO, et al. 2020 ACC/AHA guideline for the management of patients with valvular heart disease: A report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation 2021; 143:e72.
Graphic 130349 Version 2.0