Favors type 1 AIP | Favors type 2 AIP | Favors CP | Favors PDAC | Nonspecific |
Older age (>60 years) | Younger (<60 years) | Younger (<60 years) | Older (>60 years) | NA |
Male sex | Either | Either | Either | NA |
OOI* | IBD (CD or UC) | RAP, alcohol/smoking (with RAP), CFTR-RD, (TIGAR-O¶) | Past history of cancer, family cancer history, smoking | Diabetes mellitus, alcohol without AP, smoking (without AP) |
Markedly elevated IgG4 | IgG4 mildly elevated/normal | CP genetic risk factors | Somatic genetic factors | Moderately elevated IgG4 |
Diffuse CT/MRI morphology with enhancing rim | Diffuse CT/MRI morphology with enhancing rim | Diffuse distorted morphology with atrophy and calcifications | Mass lesion, invasion of adjacent structures | Atrophy, fibrosis, cystic lesions |
Small duct | Small duct | Large erratic duct with stones | Double duct sign, dilated ducts (IPMN) | NA |
Good response to steroids | Good response to steroids | No effect of steroids | No effect of steroids | NA |
Recurrence after steroids | Characteristic pain | Unexplained weight loss |
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