Electron micrograph showing lamellar inclusions in an arteriolar smooth muscle cell

Electron microscopy photomicrograph of a renal arteriole in a male patient with "classic" Fabry disease. The arrow indicates globotriaosylceramide (Gb3) inclusions in an arteriolar smooth muscle cell, while the arrowheads indicate degenerated arteriolar smooth muscle cells containing remnants of cytoplasmic organelles.