Overview of selected historical series of patients with malignant peritoneal mesothelioma treated with conventional therapies

Authors	Year	Patients (n.)	Treatment	Median survival (months)
Rogoff	1973	12	Debulking (n = 6), RT (n = 7), ip 32P (n = 4)	13
Jones	1979	7	Systemic CT (n = 2)	6
Chahinian	1982	12	Systemic CT, RT	7
Antman	1988	16	Debulking, ip cisplatin + doxorubicin, RT	16.4
Kirmani	1988	19	Ip cisplatin	12
Van Gelder	1989	19	Surgery, systemic CT*	6
Markmann	1992	19	Ip cisplatin, ip mitomycin-C (n = 18)	9
Neumann	1999	74	Not stated	12 (mean)
Etabbakh	1999	15	Debulking (n = 9), systemic CT (n = 9), ip CT (n = 1)	12.5
De Pangher	2009	81	CRS + HIPEC (n = 7), debulking (n = 23), systemic CT (n = 45)	13

All the patients underwent the listed therapies, unless otherwise specified.

RT: radiation therapy; ip: intra-peritoneal; 32P: radioactive chromic phosphate; CT: chemotherapy; CRS: cytoreductive surgery; HIPEC: hyperthermic intraperitoneal chemotherapy.
* The number of patients undergoing the listed therapies was not stated.

From: Baratti D, Kusamura S, Deraco M. Diffuse malignant peritoneal mesothelioma: systematic review of clinical management and biological research. J Surg Oncol 2011; 103:822. https://onlinelibrary.wiley.com/doi/full/10.1002/jso.21787. Copyright © 2011 John Wiley & Sons Ltd. Reproduced with permission of John Wiley & Sons Inc. This image has been provided by or is owned by Wiley. Further permission is needed before it can be downloaded to PowerPoint, printed, shared or emailed. Please contact Wiley's permissions department on [email protected] or use the RightsLink service by clicking on the 'Request Permission' link accompanying this article on Wiley Online Library (http://onlinelibrary.wiley.com).

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Overview of selected historical series of patients with malignant peritoneal mesothelioma treated with conventional therapies