SLE and comorbid NMOSD

Twenty-seven-year-old with SLE and aquaporin-4-positive NMOSD. Sagittal short-tau inversion recovery images (A, B, and C) show extensive cord hypersignal consistent with holocord myelitis. Note extension to area postrema (arrow). Patchy enhancement of thoracic cord on post-contrast T1-weighted image (D) is typical for myelitis associated with NMOSD.