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SLE and RPLS

SLE and RPLS
Seventeen-year-old with SLE and kidney transplant presents with seizures on tacrolimus. FLAIR images show classic subcortical white matter edema consistent with RPLS, predominantly involving occipital, parietal, posterior temporal, and cerebellar white matter, but also in right frontal white matter and both caudate nuclei.
FLAIR: fluid-attenuated inversion recovery; RPLS: reversible posterior leukoencephalopathy syndrome; SLE: systemic lupus erythematosus.
Courtesy of Glenn A Tung, MD, FACR.
Graphic 131131 Version 2.0

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