Calculator: VTE-BLEED score for risk of bleeding among adults receiving long-term anticoagulation

Input

	Active cancer? (2)
	Male with uncontrolled hypertension? (1)
	Anemia? (1.5)
	History of bleeding? (1.5)
	Kidney dysfunction? [creatinine clearance 30 to 60 mL/min]^* (1.5)
	Age 60 years or older? (1.5)

Result

Important: Inputs must be complete to perform calculation.


Risk score

Risk of major bleeding in the first 6 months following initial 30 days of stable anticoagulation with warfarin or initiation of dabigatran

VTE-BLEED risk score points	Bleeding risk category	Incidence of major bleeding
<2	Low risk	2.8%
≥2	Elevated risk	12.6%

Notes

*Anticoagulation with dabigatran is contraindicated for patients with estimated creatinine clearance of less than 30 mL/min.
This bleeding risk estimation tool was generated from data in patients taking warfarin (target range INR 2 to 3) or the direct thrombin inhibitor dabigatran (ie, a DOAC). The incidence of bleeding with warfarin may be higher than that associated with DOACs, which also include factor Xa inhibitors (eg, rivaroxaban, apixaban).
VTE: venous thromboembolism; INR: international normalized ratio; DOAC: direct oral anticoagulant.

References

Klok, FA, Hösel V, Clemens A, et al. Prediction of bleeding events in patients with venous thromboembolism on stable anticoagulation treatment. Eur Respir J 2016; 48:1369.

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All information contained in and produced by the EBMcalc system is provided for educational purposes only. This information should not be used for the diagnosis or treatment of any health problem or disease. THIS INFORMATION IS NOT INTENDED TO REPLACE CLINICAL JUDGMENT OR GUIDE INDIVIDUAL PATIENT CARE IN ANY MANNER. Click here for full notice and disclaimer.

Topic 131287 Version 4.0

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Calculator: VTE-BLEED score for risk of bleeding among adults receiving long-term anticoagulation