Types of HCT and risk of AKI

Donor relationship	Type of conditioning	Exposure to CNI	Risk for AKI	Development of SOS	Risk for cGVHD
Allogeneic	Myeloablative	High	19 to 66%	High	High
Allogeneic	Nonmyeloablative	High	29 to 54%	Low	High
Autologous	Myeloablative	None	12 to 50%	Moderate	None

HCT: hematopoietic cell transplantation; AKI: acute kidney injury; CNI: calcineurin inhibitor; SOS: sinusoidal obstruction syndrome; cGVHD: chronic graft-versus-host disease.

Reproduced with permission from: Hingorani S. Chronic kidney disease in long-term survivors of hematopoietic cell transplantation: epidemiology, pathogenesis, and treatment. J Am Soc Nephrol 2006; 17:1995. Copyright © 2006 American Society of Nephrology. All rights reserved.

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