Medical comorbidities |
Any potentially serious acute or chronic medical disorder (eg, involving the cardiovascular, pulmonary, renal, endocrine, hematologic, or neurologic systems; infection [eg, pneumonia, tuberculosis]) |
Mental health disorders (including substance use) |
Obesity |
Obstetric factors |
Hypertensive disorders of pregnancy |
Gestational diabetes mellitus |
Multiple gestation |
Placenta accreta spectrum, placenta previa, placental abruption |
Previous cesarean delivery |
Short interpregnancy interval |
Use of assisted reproductive technology |
Fetal anomaly, particularly those in which invasive fetal therapy is an option |
Past history of pregnancy complications (eg, preterm birth, stillbirth, fetal growth restriction) |
Nonmedical factors |
Advanced maternal age, especially age over 40 years |
Disadvantaged or vulnerable population (includes lack of health insurance coverage) |
Exposure to racism |
Exposure to interpersonal violence |
Language or literacy barriers |
Undesired pregnancy |
Provider factors |
Delays in recognition, diagnosis, or referral of high-risk patients, which may be due to poor communication, lack of adequate training/expertise, or lack of adequate resources |
Implicit bias |
Resource-limited patient care setting |
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