NCI CTCAE v5.0 maculopapular rash

Adverse event	Grade 1	Grade 2	Grade 3	Grade 4	Grade 5
Rash maculopapular	Macules/papules covering <10% BSA with or without symptoms (eg, pruritus, burning, tightness)	Macules/papules covering 10 to 30% BSA with or without symptoms (eg, pruritus, burning, tightness); limiting instrumental ADL; rash covering >30% BSA with or without mild symptoms	Macules/papules covering >30% BSA with moderate or severe symptoms; limiting self-care ADL	–	–
Definition – A disorder characterized by the presence of macules (flat) and papules (elevated). Also known as morbilliform rash, it is one of the most common cutaneous adverse events, frequently affecting the upper trunk, spreading centripetally, and associated with pruritus.

NCI CTCAE: National Cancer Institute Common Terminology Criteria for Adverse Events; BSA: body surface area; ADL: activities of daily living.

Reproduced from: Common Terminology Criteria for Adverse Events (CTCAE), Version 5.0, November 2017, National Institutes of Health, National Cancer Institute. Available at: https://ctep.cancer.gov/protocoldevelopment/electronic_applications/docs/CTCAE_v5_Quick_Reference_8.5x11.pdf (Accessed October 13, 2021).

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