Empiric antibiotic treatment for acute epididymitis in adults

Treatment should be adjusted, if needed, based on NAAT or culture results.

NAAT: nucleic acid amplification test.

* Alternative for patients unable to tolerate ceftriaxone: gentamicin 240 mg intramuscularly as a single dose (administer as two 3 mL injections) plus azithromycin 2 g orally as a single dose.

¶ Alternative for patients unable to tolerate doxycycline: azithromycin 1 g orally as a single dose (in addition to ceftriaxone).

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Empiric antibiotic treatment for acute epididymitis in adults