Determining the etiology of overt hyperthyroidism in nonpregnant, non-breastfeeding adults

Overt hyperthyroidism in nonpregnant, non-breastfeeding adults is defined by a low serum TSH with high free T4 and/or T3 (free or total T3) concentrations.

RAIU: radioactive iodine uptake; T3: triiodothyronine; T4: thyroxine; TBI/TBII: thyrotropin receptor-binding inhibitory immunoglobulin; TRAb: thyrotropin receptor antibodies; TSH: thyroid-stimulating hormone; TSI: thyroid-stimulating immunoglobulins.

* The presence of thyroid eye disease (eg, proptosis, diplopia, conjunctival inflammation, periorbital edema) alone may be sufficient to diagnose Graves' disease.

¶ There is no formal definition of moderate to severe hyperthyroidism. A total T3 >300 ng/dL and/or free T4 >3 ng/dL suggests moderate to severe disease.

Δ We obtain a baseline TSI after diagnosis of Graves' disease to guide therapy with thionamides.

Graphic 133238 Version 3.0

خرید پکیج

Determining the etiology of overt hyperthyroidism in nonpregnant, non-breastfeeding adults