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Risk of a hemoglobinopathy in a child born to one or both parents with Hb C or other beta globin gene (HBB) variants

Risk of a hemoglobinopathy in a child born to one or both parents with Hb C or other beta globin gene (HBB) variants
Refer to UpToDate topics on Hb C and reproductive counseling for additional information. Input from a hematologist or genetics expert may be appropriate.

Hb C: hemoglobin C; Hb S: sickle hemoglobin.

* Hb SC disease is a form of sickle cell disease.

¶ Various genotypes are possible.
Courtesy of Elliott P Vichinsky, MD.
Graphic 133277 Version 3.0