Histologic appearance of intraductal papillary mucinous neoplasm (IPMN) of the pancreatobiliary type

The papillary fronds of intraductal papillary mucinous neoplasm (IPMN) pancreatobiliary type are lined by high-grade dysplastic columnar cells with marked pleomorphism (arrows). Hematoxylin and eosin-stained tissue section.