Histologic features of pill-induced esophagitis and reflux esophagitis

Histologic features of esophageal mucosal epithelium in pill-induced esophagitis (A-E) and reflux esophagitis (F).
(A) Intraepithelial eosinophil infiltration with microabscess.
(B) Mixed infiltration of eosinophils and neutrophils.
(C) Intraepithelial pustules.
(D) Dilated intercellular spaces (upper), and extensive vacuolization of epithelial cells (lower).
(E) Subepithelial papillae extending three-fourths of the epithelial thickness.
(F) Reactive atypia with vesicular nucleus and prominent nucleolus (H&E stain).