Management of rapid eye movement sleep behavior disorder

REM sleep behavior disorder (RBD) occurs commonly in association with Parkinson disease, dementia with Lewy bodies, and multiple system atrophy. In younger adults (<40 years), it may occur in association with serotonergic antidepressants or narcolepsy. Spontaneous RBD in adults is often a prodromal symptom of Parkinson disease or related alpha-synuclein neurodegenerative disorders. Refer to UpToDate clinical content for further details and discussion of prognostic disclosure and counseling.