Tips for administering isotretinoin to children

Keep out of direct sunlight, use capsule immediately after removing from packaging

Capsule can be swallowed whole or chewed

Poke a hole in capsule with sharp knife or nail clippers and add to food (note, capsule is very tough)

The capsule may be softened by placing in a small cup with warm water or milk for 2 to 3 minutes

Add to limited amount (1 oz) of breast milk or formula for infants

Give with high-fat food (eg, whole milk, ice cream, peanut or other nut butter) for best absorption

Freeze capsule in bite-sized, soft-centered chocolate and chew chocolate and capsule

From: Zaenglein AL, Levy ML, Stefanko NS, et al. Consensus recommendations for the use of retinoids in ichthyosis and other disorders of cornification in children and adolescents. Pediatr Dermatol 2021; 38:164. https://onlinelibrary.wiley.com/doi/10.1111/pde.14408. Copyright © 2021 Wiley Periodical, Inc. Reproduced with permission of John Wiley & Sons Inc. This image has been provided by or is owned by Wiley. Further permission is needed before it can be downloaded to PowerPoint, printed, shared or emailed. Please contact Wiley's permissions department either via email: [email protected] or use the RightsLink service by clicking on the 'Request Permission' link accompanying this article on Wiley Online Library (https://onlinelibrary.wiley.com/). Table originally adapted from: https://www.stjude.org/treatment/patient-resources/caregiver-resources/medicines/a-z-list-of-medicines/isotretinoin.html.

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Tips for administering isotretinoin to children