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خرید پکیج
تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
نسخه الکترونیک
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Recommended wait time for SOT candidates with a prior history of melanoma

Recommended wait time for SOT candidates with a prior history of melanoma
Pathological stage 5-year MS (%) Appropriate treatment pretransplantation Time interval to transplant Additional considerations
In situ 99 Wide local excision No wait time necessary Follow-up 3 months post-SOT
Stage IA (T1a) 99 Wide local excision 1 year  
Stage IB (T1b or T2a) 97 Wide local excision plus SLNB 1 year If positive SLNB at time of diagnosis, imaging as for Stage IIA disease
Stage IIA (T2b or T3a) 94 Wide local excision plus SLNB 1 year

Imaging of the brain, CAP

Imaging of the neck for those with head/neck melanoma primary
Stage IIB (T3b or T4a) 87 Wide local excision plus SLNB 2 to 4 years Imaging as above
Stage IIC (T4b) 82 Wide local excision plus SLNB 2 to 4 years Imaging as above
Stage IIIA (T1-2a, N1a or 2a) 93 Wide excision plus SLNB plus lymph node dissection 1 ton 2 years

Imaging as above

Oncology referral
Stage IIIB (T0-3a and N1a/b/c, N2a/b) 83

Wide excision plus SLNB plus lymph node dissection

Adjuvant therapy with CKI
2 to 4 years

Imaging as above

Oncology referral
Stage IIIC (T3b-4b and N2b/c-N3b/c) 69

Wide excision plus SLNB plus lymph node dissection

Adjuvant therapy with CKI
At least 5 years

Imaging as above

Oncology referral (no consensus was possible for this group)
Stage IIID (T4b and N3a-3c) 32

Wide excision plus SLNB plus lymph node dissection

Adjuvant therapy with CKI
At least 5 years Oncology referral (no consensus was possible for this group)
Stage IV 15 to 20

Wide excision plus SLNB plus lymph node dissection

Adjuvant therapy with CKI
At least 5 years Oncology referral (no consensus was possible for this group)
MSS: melanoma-specific survival; SLNB: sentinel lymph node biopsy; CKI: checkpoint inhibitor; CAP: chest, abdomen, and pelvis.
From: Al-Adra DP, Hammel L, Roberts J, et al. Preexisting melanoma and hematological malignancies, prognosis, and timing to solid organ transplantation: A consensus expert opinion statement. Am J Transplant 2021; 21:475. https://onlinelibrary.wiley.com/doi/10.1111/ajt.16324. Copyright © 2021 John Wiley & Sons Ltd. Reproduced with permission of John Wiley & Sons Inc. This image has been provided by or is owned by Wiley. Further permission is needed before it can be downloaded to PowerPoint, printed, shared or emailed. Please contact Wiley's permissions department either via email: [email protected] or use the RightsLink service by clicking on the 'Request Permission' link accompanying this article on Wiley Online Library (https://onlinelibrary.wiley.com/).
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