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Sirolimus gel (topical): Patient drug information

Sirolimus gel (topical): Patient drug information

(For additional information see "Sirolimus gel (topical): Drug information" and see "Sirolimus gel (topical): Pediatric drug information")

You must carefully read the "Consumer Information Use and Disclaimer" below in order to understand and correctly use this information.

Brand Names: US
  • Hyftor
What is this drug used for?
  • It is used to treat a skin problem called angiofibroma.
What do I need to tell my doctor BEFORE I take this drug?
  • If you are allergic to this drug; any part of this drug; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
  • If you are breast-feeding. Do not breast-feed while you take this drug.
  • This is not a list of all drugs or health problems that interact with this drug.
  • Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take this drug?
  • Tell all of your health care providers that you take this drug. This includes your doctors, nurses, pharmacists, and dentists.
  • Talk with your doctor before getting any vaccines after getting this drug. Vaccine use after getting this drug may make the vaccine not work as well.
  • If possible, make sure all vaccines are up to date before treatment with this drug.
  • Avoid sun, sunlamps, and tanning beds while you use this drug. Avoid these things even when this drug is not on your skin. Talk with your doctor about ways to protect your skin from the sun.
  • Do not have any kind of light therapy while you are using this drug.
  • This drug may affect fertility. Fertility problems may lead to not being able to get pregnant or father a child. If you plan to get pregnant or father a child, talk with your doctor before taking this drug.
  • This drug may cause harm to the unborn baby if you take it while you are pregnant.
  • If you may become pregnant, you must use birth control while taking this drug and for some time after the last dose. Ask your doctor how long to use birth control. If you get pregnant, call your doctor right away.
What are some side effects that I need to call my doctor about right away?
  • WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Chest pain.
  • Dizziness or passing out.
  • This drug also has forms that are taken by mouth. Severe and sometimes deadly effects have happened with these forms. These have included allergic reactions, high cholesterol, high triglyceride levels, lung problems, and infection (including a brain infection called PML). Rare cases of cancer like lymphoma or skin cancer have also happened. Talk with the doctor if you have any questions.
  • Call your doctor right away if you have any signs of these effects. This may include confusion, memory problems, depression, behavior change, weakness, trouble speaking or thinking, change in balance, change in eyesight, cough, shortness of breath, or trouble breathing. It may also include a skin lump or growth; change in the color or size of a mole; weight loss; night sweats; swollen glands; or signs of infection like fever, chills, or sore throat.
What are some other side effects of this drug?
  • All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
  • Eye redness.
  • It is common to have skin irritation with this drug. Skin irritation may include dry skin, redness, itching, or acne. Call your doctor if you have skin irritation that is severe, bothers you, or does not go away.
  • These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
  • You may report side effects to your national health agency.
How is this drug best taken?
  • Use this drug as ordered by your doctor. Read all information given to you. Follow all instructions closely.
  • Do not take this drug by mouth. Use on your skin only. Keep out of your mouth, nose, and eyes (may burn).
  • Do not put in the vagina.
  • Wash your hands before and after use.
  • Put a thin layer on the affected part and rub in gently.
  • Do not put on healthy skin.
  • Do not use coverings (bandages, dressings) unless told to do so by the doctor.
What do I do if I miss a dose?
  • Put on a missed dose as soon as you think about it.
  • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
  • Do not put on 2 doses at the same time or extra doses.
How do I store and/or throw out this drug?
  • Store in a refrigerator. Do not freeze.
  • Protect from light.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
General drug facts
  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Last Reviewed Date2022-04-29
Consumer Information Use and Disclaimer
  • This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential diagnostic and treatment options. It does NOT include all information about conditions, treatments, medications, side effects, or risks that may apply to a specific patient. It is not intended to be medical advice or a substitute for the medical advice, diagnosis, or treatment of a health care provider based on the health care provider's examination and assessment of a patient's specific and unique circumstances. Patients must speak with a health care provider for complete information about their health, medical questions, and treatment options, including any risks or benefits regarding use of medications. This information does not endorse any treatments or medications as safe, effective, or approved for treating a specific patient. UpToDate, Inc. and its affiliates disclaim any warranty or liability relating to this information or the use thereof. The use of this information is governed by the Terms of Use, available at https://www.wolterskluwer.com/en/know/clinical-effectiveness-terms.
  • © 2024 UpToDate, Inc. and its affiliates and/or licensors. All rights reserved.
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