Granular deposits in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL)

Electron microscopy of skin biopsy shows electron-dense granular deposits (arrows) in the basal lamina surrounding vascular smooth muscle cells.

Reproduced with permission from: Smith BW, Henneberry J, Connolly T. Skin biopsy findings in CADASIL. Neurology 2002; 59(6):961. Copyright © 2002 American Academy of Neurology and Wolters Kluwer Health, Inc. https://n.neurology.org/.

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Granular deposits in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL)