Classification of severity of acute SARS-CoV-2 infection in children[1]
Classification of severity of acute SARS-CoV-2 infection in children[1]
Severity classification
Description
Mild or moderate
No new or increased supplemental oxygen requirements
Severe
New requirement for supplemental oxygen, or
Increased supplemental oxygen requirement from baseline without new or increased need for ventilatory support (noninvasive or invasive)
Critical
New or increased need for noninvasive or invasive mechanical ventilation
Sepsis
Multiorgan failure
Rapidly worsening clinical trajectory
This table summarizes the severity classification for acute SARS-CoV-2 infection provided in the multicenter interim guidance on use of antivirals for children with COVID-19.[1] Other experts may use a different severity classification. Refer to UpToDate content on COVID-19 or MIS-C in children for additional information.
SARS-CoV-2: severe acute respiratory syndrome coronavirus 2; COVID-19: coronavirus disease 2019; MIS-C: multisystem inflammatory syndrome in children.
Reference:
Chiotos K, Hayes M, Kimberlin DW, et al. Multicenter interim guidance on use of antivirals for children with coronavirus disease 2019/severe acute respiratory syndrome coronavirus 2. J Pediatric Infect Dis Soc 2021; 10:34.
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