Version June 2024
| The definitions of the T categories correspond to the stages accepted by the Fédération Internationale de Gynécologie et d'Obstétrique (FIGO). Both systems are included for comparison. | |||
| Primary tumor (T)* | |||
| T category | FIGO stage | T criteria | |
| TX | Primary tumor cannot be assessed | ||
| T0 | No evidence of primary tumor | ||
| T1 | I | Carcinoma is strictly confined to the cervix (extension to the corpus should be disregarded) | |
| T1a | IA | Invasive carcinoma that can be diagnosed only by microscopy with maximum depth of invasion ≤5 mm | |
| T1a1 | IA1 | Measured stromal invasion ≤3 mm in depth | |
| T1a2 | IA2 | Measured stromal invasion >3 mm and ≤5 mm in depth | |
| T1b | IB | Invasive carcinoma with measured deepest invasion >5 mm (greater than stage IA); lesion limited to the cervix uteri with size measured by maximum tumor diameter. NOTE: The involvement of vascular/lymphatic spaces should not change the staging. The lateral extent of the lesion is no longer considered. | |
| T1b1 | IB1 | Invasive carcinoma >5 mm depth of stromal invasion and ≤2 cm in greatest dimension | |
| T1b2 | IB2 | Invasive carcinoma >2 cm and ≤4 cm in greatest dimension | |
| T1b3 | IB3 | Invasive carcinoma >4 cm in greatest dimension | |
| T2 | II | Carcinoma invades beyond the uterus, but has not extended onto the lower third of the vagina or to the pelvic wall | |
| T2a | IIA | Involvement limited to the upper two-thirds of the vagina without parametrial invasion | |
| T2a1 | IIA1 | Invasive carcinoma ≤4 cm in greatest dimension | |
| T2a2 | IIA2 | Invasive carcinoma >4 cm in greatest dimension | |
| T2b | IIB | With parametrial invasion but not up to the pelvic wall | |
| T3 | III | Carcinoma involves the lower third of the vagina and/or extends to the pelvic wall and/or causes hydronephrosis or nonfunctioning kidney. NOTE: The pelvic wall is defined as the muscle, fascia, neurovascular structures, and skeletal portions of the bony pelvis. Cases with no cancer-free space between the tumor and pelvic wall by rectal examination are FIGO III. | |
| T3a | IIIA | Carcinoma involves lower third of the vagina, with no extension to the pelvic wall | |
| T3b | IIIB | Extension to the pelvic wall and/or hydronephrosis or nonfunctioning kidney (unless known to be due to another cause) | |
| T4 | IVA | Carcinoma has involved (biopsy-proven) the mucosa of the bladder or rectum, or has spread to adjacent organs. (Bullous edema, as such, does not permit a case to be assigned to stage IVA.) | |
Primary tumor suffix
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| The definitions of the N categories correspond to the stages accepted by the Fédération Internationale de Gynécologie et d'Obstétrique (FIGO). Both systems are included for comparison. | |||
| Regional lymph nodes (N)* | |||
| N category | FIGO stage | N criteria | |
| NX | Regional lymph nodes cannot be assessed | ||
| N0 | No regional lymph node metastasis | ||
| N0(i+) | Isolated tumor cells in regional lymph node(s) ≤0.2 mm, or single cells or clusters of cells ≤200 cells in a single lymph node cross section | ||
| N1 | IIIC1 | Regional lymph node metastasis to pelvic lymph nodes only | |
| N1mi | IIIC1 | Regional lymph node metastasis (>0.2 mm but ≤2.0 mm in diameter) to pelvic lymph nodes | |
| N1a | IIIC1 | Regional lymph node metastasis (>2.0 mm in diameter) to pelvic lymph nodes | |
| N2 | IIIC2 | Regional lymph node metastasis to para-aortic lymph nodes, with or without positive pelvic lymph nodes | |
| N2mi | IIIC2 | Regional lymph node metastasis (>0.2 mm but ≤2.0 mm in diameter) to para-aortic lymph nodes, with or without positive pelvic lymph nodes | |
| N2a | IIIC2 | Regional lymph node metastasis (>2.0 mm in diameter) to para-aortic lymph nodes, with or without positive pelvic lymph nodes | |
| NOTE: Suffix (f) is added to the N category when metastasis is identified only by FNA or core biopsy. Suffix (sn) is added to the N category when metastasis is identified only by sentinel lymph node biopsy. | |||
Regional lymph nodes suffix
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| The definitions of the M categories correspond to the stages accepted by the Fédération Internationale de Gynécologie et d'Obstétrique (FIGO). Both systems are included for comparison. | |||
| Distant metastasis (M)* | |||
| M category | FIGO stage | M criteria | |
| M0 | No distant metastasis | ||
| cM1 | IVB | Distant metastasis (includes metastasis to inguinal lymph nodes, intraperitoneal disease, lung, liver, or bone) (excludes metastasis to pelvic or para-aortic lymph nodes, or vagina) | |
| pM1 | IVB | Microscopic confirmation of distant metastasis (includes metastasis to inguinal lymph nodes, intraperitoneal disease, lung, liver, or bone) (excludes metastasis to pelvic or paraaortic lymph nodes, or vagina) | |
| AJCC prognostic stage group is assigned based on the stage classification and categories chosen.* | |||
| Prognostic stage groups | |||
| When T is... | And N is... | And M is... | Then the stage group is... |
| T1 | N0 | M0 | I |
| T1a | N0 | M0 | IA |
| T1a1 | N0 | M0 | IA1 |
| T1a2 | N0 | M0 | IA2 |
| T1b | N0 | M0 | IB |
| T1b1 | N0 | M0 | IB1 |
| T1b2 | N0 | M0 | IB2 |
| T1b3 | N0 | M0 | IB3 |
| T2 | N0 | M0 | II |
| T2a | N0 | M0 | IIA |
| T2a1 | N0 | M0 | IIA1 |
| T2a2 | N0 | M0 | IIA2 |
| T2b | N0 | M0 | IIB |
| T3 | N0 | M0 | III |
| T3a | N0 | M0 | IIIA |
| T3b | N0 | M0 | IIIB |
| TX, T0, T1-3 | N1 | M0 | IIIC1 |
| TX, T0, T1-3 | N2 | M0 | IIIC2 |
| T4 | Any N | M0 | IVA |
| Any T | Any N | M1 | IVB |
TNM: tumor, node, metastasis; AJCC: American Joint Committee on Cancer; UICC: International Union Against Cancer.
* AJCC data elements required for staging are identified with an asterisk.آیا می خواهید مدیلیب را به صفحه اصلی خود اضافه کنید؟
