CDC surveillance definition for health care-associated meningitis and ventriculitis^[1]

At least one of the following criteria:

Organism(s) identified from CSF by a culture or non-culture-based microbiologic testing method*

The following features are present
- At least two of the following:
  - Fever (>38.0°C) or headache^¶
  - Meningeal sign(s) with no other recognized cause
  - Cranial nerve sign(s) with no other recognized cause
- And at least one of the following:
  - Increased white cells, elevated protein, and decreased glucose in CSF
  - Organism(s) seen on Gram stain of CSF
  - Organism(s) identified from blood by a culture or non-culture based microbiologic testing method
  - Diagnostic single antibody titer (IgM) or fourfold increase in paired sera (IgG) for organism

CDC: United States Centers for Disease Control and Prevention; CSF: cerebrospinal fluid.

* Only when testing is performed for purposes of clinical diagnosis or treatment, and not, for example, active surveillance culture/testing.

¶ For patients ≤1 year of age, this clinical criteria can be met by fever (>38.0°C), hypothermia (<36.0°C), apnea, bradycardia, or irritability without other recognized cause.

Reference:

Centers for Disease Control and Prevention. CDC/NHSN Surveillance Definitions for Specific Types of Infections. Available at: https://www.cdc.gov/nhsn/pdfs/pscmanual/17pscnosinfdef_current.pdf (Accessed on January 30, 2023).

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CDC surveillance definition for health care-associated meningitis and ventriculitis[1]

CDC surveillance definition for health care-associated meningitis and ventriculitis^[1]