Version June 2024
| Gene | Gene locus MIM# | Function | Localization of defect | Disease | Inheritance | Initial molecular characterization (PMID) |
| PI glycan anchor biosynthesis class A (PIGA) | 311770 | GlcNAc-transferase complex, catalytic subunit (transfers GlcNAc to PI) | ER (cytosolic side) | MCAHS2 (GPIBD4, EIEE20) | XL | 22305531 |
| PI glycan anchor biosynthesis class C (PIGC) | 601730 | GlcNAc-transferase complex | ER (cytosolic side) | PIGC-CDG | AR | 27694521 |
| PI glycan anchor biosynthesis class Q (PIGQ) | 605754 | GlcNAc-transferase complex | ER (cytosolic side) | PIGQ-CDG | AR | 24463883 |
| PI glycan anchor biosynthesis class P (PIGP) | 605938 | GlcNAc-transferase complex | ER (cytosolic side) | EIEE55 (GPIBD14) | AR | 28334793 |
| PI glycan anchor biosynthesis class Y (PIGY) | 610662 | GlcNAc-transferase complex | ER (cytosolic side) | HPMRS6 (GPIBD12) | AR | 26293662 |
| PI glycan anchor biosynthesis class H (PIGH) | 600154 | GlcNAc-transferase complex | ER (cytosolic side) | PIGH-CDG | AR | 29573052, 29603516 |
| PI glycan anchor biosynthesis class L (PIGL) | 605947 | GlcNAc-PI de-N-acetylase (GlcNAc-PI to GlcN-PI) | ER (cytosolic side) | CHIME syndrome (GPIBD5) | AR | 22444671 |
| PI glycan anchor biosynthesis class W (PIGW) | 610275 | Inositol acyltransferase (transfers fatty acid to GlcN-PI) | ER (luminal side) | HPMRS5 (GPIBD11) | AR | 24367057 |
| PI glycan anchor biosynthesis class M (PIGM) | 610273 | Man-transferase 1 (transfers mannose to GlcN-aPI) | ER (luminal side) | GPIBD1 | AR | 16767100 |
| PI glycan anchor biosynthesis class V (PIGV) | 610274 | Man-transferase 2 (transfers mannose to ManGlcN-aPI) | ER (luminal side) | HPMRS1 (GPIBD2) | AR | 20802478 |
| PI glycan anchor biosynthesis class N (PIGN) | 606097 | EtNP-transferase 1 (transfers EtNP to ManManGlcN-aPI) | ER (luminal side) | MCAHS1 (GPIBD3) | AR | 21493957 |
| PI glycan anchor biosynthesis class B (PIGB) | 604122 | Man-transferase 3 (transfers mannose to Man(etNP)ManGlcN-aPI) | ER (luminal side) | PIGB-CDG | AR | 31256876 |
| PI glycan anchor biosynthesis class O (PIGO) | 614730 | EtNP-transferase 3 (transfers EtNP to ManMan(EtNP)ManGlcN-aPI) | ER (luminal side) | HPMRS2 (GPIBD6) | AR | 22683086 |
| PI glycan anchor biosynthesis class G (PIGG) | 616918 | EtNP-transferase 2 (transfers EtNP to EtNPManMan(EtNP) ManGlcN-aPI) | ER (luminal side) | MRT53 (GPIBD13) | AR | 26996948 |
| PI glycan anchor biosynthesis class T (PIGT) | 610272 | GPI transamidase (transfers protein to GPI anchor) | ER (luminal side) | MCAHS3 (GPIBD7) | AR | 23636107 |
| PI glycan anchor biosynthesis class S (PIGS) | 610271 | GPI transamidase (transfers protein to GPI anchor) | ER (luminal side) | PIGS-CDG | AR | 30269814 |
| PI glycan anchor biosynthesis class U (PIGU) | 608528 | GPI transamidase (transfers protein to GPI anchor) | ER (luminal side) | PIGU-CDG | AR | 31353022 |
| PI glycan anchor biosynthesis class K (PIGK) | 605087 | GPI transamidase (transfers protein to GPI anchor) | ER (luminal side) | PIGK-CDG | AR | 32220290 |
| Post-GPI attachment to proteins inositol deacylase 1 (PGAP1) | 611655 | Inositol deacylase (removes fatty acid) | ER (luminal side) | MRT42 (GPIBD9) | AR | 24784135 |
| Post-GPI attachment to proteins phospholipase 3 (PGAP3) | 611801 | Phospholipase A2 (removes unsaturated fatty acid at sn-2 [the middle position of the glycerol backbone]) | Golgi | HPMRS4 (GPIBD10) | AR | 24439110 |
| Post-GPI attachment to proteins 2 (PGAP2) | 615187 | Reacylates sn-2 with stearic acid | Golgi | HPMRS3 (GPIBD8) | AR | 23561846, 23561847 |
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