Brain MRI in a neonate with congenital HSV-2 infection

Congenital HSV-2 infection may cause various types of brain malformations. This brain MRI of an infant with congenital HSV-2 infection shows diffuse cortical dysplasia with porencephalic cystic changes and focal encephalomalacia, most notably in the right parietal lobe (panels B and C). There are also punctate calcifications posteriorly (panel A).