Example of nurse administered IV opioid orders for postoperative pain outside of the PACU

Drug	Concentration*	Dose range	Dose interval
Hydromorphone	0.2 mg/mL	0.2 to 0.5 mg	Every 1 to 3 hours as needed
Morphine	1 mg/mL	1 to 3 mg	Every 1 to 3 hours as needed
Fentanyl	50 mcg/mL	25 to 50 mcg	Every 0.5 to 3 hours as needed
Oliceridine	1 mg/mL	1 to 3 mg	Every 1 to 3 hours as needed^¶

Hospitals often require nurse administered pain medication orders to include a pain level threshold and recommend IV opioid use for severe pain (eg, 8 to 10 on a 0 to 10 pain assessment scale).

PACU: post anesthesia care unit.

* Typical concentrations listed; others are available. Carefully check concentration of locally available product(s).

¶ After initial two hourly doses (1.5 mg and 0.75 mg if needed), oliceridine dose may be repeated at intervals of no less than one hour as needed and titrated based on response and tolerability to a maximum of 3 mg per dose; maximum cumulative dose is 27 mg in 24 hours.

Graphic 140313 Version 3.0

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Example of nurse administered IV opioid orders for postoperative pain outside of the PACU