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خرید پکیج
تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
نسخه الکترونیک
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Determinants of systemic oxygenation and carbon dioxide removal during ECLS

Determinants of systemic oxygenation and carbon dioxide removal during ECLS
Oxygenation CO2 removal
Blood flow rate (L/minute; ie, blood flow entering membrane from the pump) Sweep gas flow rate (L/minute; ie, fresh gas [mix of oxygen and air] flowing into the membrane)
Blood flow:cardiac output ratio*

Blood flow rate (L/minute) (ie, blood flow entering membrane from the pump)

CO2 removal will be more dependent on blood flow rate at lower flow rates (eg, <3 L/minute)

Diffusion properties of the membrane

Membrane lung surface area and design

Diffusion properties of the membrane

Membrane lung surface area and design
Native lung gas exchangeΔ Native lung gas exchangeΔ
Degree of recirculation Partial pressure of CO2 entering the membrane lung
Dual circulation/competitive flow phenomenon§  
Bolded text = main determinants of this function.

ECLS: extracorporeal life support; V-V: venovenous; ECMO: extracorporeal membrane oxygenation; V-A: venoarterial.

* Applies only to V-V ECMO.

¶ Different membrane materials have different diffusion properties and diffusion can be affected by processes such as thrombus.

Δ This may vary and represent that achieved through mechanical ventilation or that achieved with spontaneous ventilation.

◊ Applies only to V-V ECMO, particularly when using a 2-site approach.

§ Applies to V-A ECMO only (refer to UpToDate topics on extracorporeal membrane oxygenation).
Graphic 140684 Version 1.0

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