Although often correlated, peak flow and FEV1 may be uncoupled, with peak flow severely underestimating asthma severity. Above are flow-volume and volume-time loops in a patient with preserved peak flow (peak of flow-volume loop) but profound obstruction (FEV1/FVC <0.5, FEV1 44% predicted, plateau FVC not achieved after 10 seconds).
FEV1: forced expiratory volume in one second; FEV3: forced expiratory volume in three seconds; FVC: forced vital capacity; FET: forced expiratory time.
Courtesy of Christopher H Fanta, MD.
Graphic 141036 Version 1.0
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