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خرید پکیج

تعداد آیتم قابل مشاهده باقیمانده : 3 مورد

Treatment of drug-resistant leprosy in adults

Treatment of drug-resistant leprosy in adults

	First six months	Next 18 months
	Combination therapy with one of the following regimens:
Rifampin resistance	Ofloxacin* 400 mg orally once daily, plus Minocycline 100 mg orally once daily, plus Clofazimine 50 mg orally once daily	Ofloxacin* 400 mg orally once daily, plus Clofazimine 50 mg orally once daily OR Minocycline 100 mg orally once daily, plus Clofazimine 50 mg orally once daily
	OR
	Ofloxacin* 400 mg orally once daily, plus Clarithromycin 500 mg orally once daily, plus Clofazimine 50 mg orally once daily	Ofloxacin* 400 mg orally once daily, plus Clofazimine 50 mg orally once daily
Rifampin and ofloxacin resistance	Clarithromycin 500 mg orally once daily, plus Minocycline 100 mg orally once daily, plus Clofazimine 50 mg orally once daily	Clarithromycin 500 mg orally once daily, plus Clofazimine 50 mg orally once daily OR Minocycline 100 mg orally once daily, plus Clofazimine 50 mg orally once daily

* Alternatives to ofloxacin include levofloxacin (500 mg orally once daily for patients with normal kidney function) or moxifloxacin (400 mg orally once daily).

Reference:

World Health Organization. Guidelines for the Diagnosis, Treatment and Prevention of Leprosy. https://apps.who.int/iris/bitstream/handle/10665/274127/9789290226383-eng.pdf?ua=1 (Accessed on March 23, 2023).

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