Insomnia medication clinical use and prescribing considerations

Pharmacotherapy should not be the sole therapy for insomnia. Cognitive behavioral therapy for insomnia (CBT-I) is the recommended first-line treatment for chronic insomnia. This table is intended to complement individualized decision-making for medication selection. Appropriate clinical use may differ from the US Food and Drug Administration approved indication(s) for a given drug. Refer to UpToDate topics on insomnia treatment for more detailed discussion.