Stages of type 1 diabetes^[1]

Stage 1*

2 or more autoantibodies

Presymptomatic

Normoglycemia

Stage 2

2 or more autoantibodies

Presymptomatic

Dysglycemia:

Fasting glucose 100 to 125 mg/dL (5.6 to 6.9 mmol/L)
2-hour postprandial glucose 140 to 199 mg/dL (7.8 to 11.1 mmol/L)
A1C 5.7 to 6.4%

Stage 3

Autoantibodies may become absent

Symptomatic (usually but not uniformly)

Overt hyperglycemia, meets ADA diagnostic criteria for diabetes

A1C: glycated hemoglobin; ADA: American Diabetes Association.

* Virtually all individuals with stage 1 type 1 diabetes will progress to stage 3 type 1 diabetes, approximately 35% within 5 years, 70% within 10 years, and >95% within 15 years.

Reference:

Insel RA, Dunne JL, Atkinson MA, et al. Staging presymptomatic type 1 diabetes: A scientific statement of JDRF, the Endocrine Society, and the American Diabetes Association. Diabetes Care 2015; 38:1964.

Graphic 141622 Version 1.0

خرید پکیج

Stages of type 1 diabetes[1]

Stages of type 1 diabetes^[1]