Skin necrosis after repeated xylazine injection

Large tissue loss and necrosis on the shins of a patient who injected heroin and illicit fentanyl laced with xylazine on a daily basis.

Reproduced with permission from: Ehrman-Dupre R, Kaigh C, Salzman M, et al. Management of xylazine withdrawal in a hospitalized patient: A case report. J Addict Med 2022; 16(5):595-598. Copyright © 2022 American Society of Addiction Medicine. https://journals.lww.com/journaladdictionmedicine/pages/default.aspx.

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Skin necrosis after repeated xylazine injection