Initiate combination therapy to cover gram-positive and gram-negative organisms* |
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* We administer antifungal prophylaxis to patients on peritoneal dialysis who are treated with antibiotics for longer than 3 days; other experts do so for any antibiotic course longer than 1 day. For details, refer to UpToDate content on fungal peritonitis in peritoneal dialysis.
¶ We use vancomycin for empiric gram-positive coverage because the majority of coagulase-negative staphylococci are resistant to beta-lactams, as are many Staphylococcus aureus isolates. In centers where methicillin-resistant S. aureus (MRSA) rates are low, some experts use intraperitoneal cefazolin because many coagulase-negative staphylococci reported as resistant to beta-lactams are susceptible at the high cefazolin concentrations achieved in peritoneal fluid.
Δ Once susceptibility results are available, we switch to a non-aminoglycoside class of antibiotics, if possible, to prevent ototoxicity.آیا می خواهید مدیلیب را به صفحه اصلی خود اضافه کنید؟