Version July 2025
* There is no consensus on the optimal timing and duration of antifungal prophylaxis. We administer antifungal prophylaxis if antibiotics are administered for longer than 3 days. Refer to UpToDate content on risk factors and prevention of peritonitis in peritoneal dialysis for details.
¶ In the case of penicillin allergy, treat with trimethoprim/sulfamethoxazole or clindamycin orally.
Δ Patients with resolving exit-site or tunnel infections are typically evaluated at least every 2 weeks.
◊ Antibiotics should be continued for 1 to 2 weeks after catheter removal. Refer to UpToDate topic on peritoneal catheter exit-site and tunnel infections in peritoneal dialysis in adults for details.
§ Catheter removal or other surgical intervention is often indicated for refractory infection. Management depends on physical examination findings, ultrasound imaging results, and the availability of catheter salvage procedures. Refer to UpToDate topic on peritoneal catheter exit-site and tunnel infections in peritoneal dialysis in adults for details.