| Agent | Recommended dosing interval | Manufacturer recommendations for missed doses |
| Short-acting agents |
| Exenatide | Twice daily | - Skip missed dose and resume at the next scheduled dose.
|
| Lixisenatide | Once daily | - If a dose is missed, administer within 1 hour prior to next meal.
|
| Long-acting agents |
| Dulaglutide | Once weekly | - Administer as soon as possible if there are ≥3 days (72 hours) until next scheduled dose.
- If <3 days before next scheduled dose, skip the missed dose and administer on the next scheduled day.
|
| Exenatide extended release | Once weekly | - Administer as soon as possible if there are ≥3 days (72 hours) until the next scheduled dose.
- If <3 days before next scheduled dose, skip the missed dose and administer on the next scheduled day.
|
| Liraglutide | Once daily | - If dose is missed, resume with the next scheduled dose.
|
| Semaglutide (injectable) | Once weekly | - Administer as soon as possible within 5 days after the missed dose.
- If >5 days have passed, skip the dose and administer on the next scheduled day.
|
| Semaglutide (oral) | Once daily | - If dose is missed, resume with the next scheduled dose.
|
| Tirzepatide | Once weekly | - Administer as soon as possible within 4 days (96 hours) after the missed dose.
- If >4 days have passed, skip the dose and administer on the next scheduled day.
|
