Paroxysmal nocturnal hemoglobinuria: Management

This algorithm describes management of PNH. Refer to related UpToDate material for details of diagnosis, PNH categories, symptom management, supportive care, eligibility for allogeneic HCT, immunosuppressive therapy, and monitoring for and management of breakthrough hemolysis.

ANC: absolute neutrophil count; BM: bone marrow; BMF: bone marrow failure; HCT: hematopoietic cell transplantation; microL: microliter; PNH: paroxysmal nocturnal hemoglobinuria; RBC: red blood cell.

* Refer to related UpToDate material for details of monitoring for disease progression.

¶ Other complement inhibitors may be acceptable, as described in related UpToDate material. Monitor for breakthrough hemolysis.

Graphic 146482 Version 1.0

خرید پکیج

Paroxysmal nocturnal hemoglobinuria: Management