BSA: body surface area; cGVHD: chronic graft-versus-host disease; GI: gastrointestinal; NIH: National Institutes of Health; SR-cGVHD: steroid-refractory cGVHD.
* The cGVHD severity score is based on a modified NIH scoring system, which includes assessment of skin, mouth, eyes, GI tract, liver, lungs, joints/fascia, and genital tract. Scoring of severity at each involved site and determination of the overall severity score are discussed in related UpToDate material.
¶ Preferred topical treatments vary according to site(s) of involvement (eg, skin, oral mucosa, etc).
Δ Some experts favor systemic prednisone alone for severe cGVHD.