LVEF: left ventricular ejection fraction; MR: mitral regurgitation; MV: mitral valve; TEER: transcatheter edge-to-edge repair.
* For most patients undergoing MV surgery for secondary MR, MV replacement with chordal sparing is preferred to MV repair.
¶ Optimized heart failure management includes evidence-based pharmacologic therapy and cardiac resynchronization therapy, as indicated.
Δ Contraindications to TEER include known hypersensitivity to clip components (nickel/titanium, cobalt, chromium, polyester), contrast sensitivity, active endocarditis on the MV, or rheumatic MV disease.
◊ Refer to UpToDate content on MV surgery for selected patients with secondary MR with refractory symptoms.