Inborn error of immunity germline mutations associated with cancer
Inborn error of immunity germline mutations associated with cancer
Many of the known genes associated with somatic mutations in adult-onset cancer patients (https://cancer.sanger.ac.uk/cosmic) overlap with known IEI germline mutations associated with early-onset cancer in children.
COSMIC: Catalogue of Somatic Mutations in Cancer; IEI: inborn errors of immunity.
