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Thymic tumors TNM staging AJCC version 9

Thymic tumors TNM staging AJCC version 9
Primary tumor (T)*
T category T criteria
TX Primary tumor cannot be assessed
T0 No evidence of primary tumor
T1 Tumor limited to the thymus with or without encapsulation, or directly invades into the mediastinal fat only, or directly invades the mediastinal pleura but does not involve any other mediastinal structure
T1a Tumor ≤5 cm in greatest dimension with either:
  • Limited to the thymus with or without encapsulation
  • Directly invades into the mediastinal fat only
  • Directly invades the mediastinal pleura but does not involve any other mediastinal structure
T1b Tumor >5 cm in greatest dimension with either:
  • Limited to the thymus with or without encapsulation
  • Directly invades into the mediastinal fat only
  • Directly invades the mediastinal pleura but does not involve any other mediastinal structure
T2 Tumor with direct invasion of the pericardium (either partial or full thickness), or the lung, or the phrenic nerve
T3 Tumor with direct invasion into any of the following: brachiocephalic vein, superior vena cava, chest wall, or extrapericardial pulmonary arteries or veins
T4 Tumor with direct invasion into any of the following: aorta (ascending, arch, or descending), arch vessels, intrapericardial pulmonary artery or veins, myocardium, trachea, esophagus
Primary tumor suffix
  • (m) Multiple synchronous primary tumors
Regional lymph nodes (N)*
N category N criteria
NX Regional lymph nodes cannot be assessed
N0 No tumor involvement of regional lymph node(s)
N1 Tumor involvement of anterior (perithymic) lymph nodes
N2 Tumor involvement of deep intrathoracic or cervical lymph nodes (eg, paratracheal, subcarinal, aortopulmonary window, hilar, jugular, and/or supraclavicular nodes)
Regional lymph nodes suffix
  • (f) FNA or core needle biopsy
Distant metastasis (M)*
M category M criteria
cM0 No distant metastasis
cM1 Distant metastasis
cM1a Separate pleural or pericardial nodule(s)
cM1b Pulmonary intraparenchymal nodule or other distant metastasis
pM1 Microscopic confirmation of distant metastasis
pM1a Microscopic confirmation of separate pleural or pericardial nodule(s)
pM1b Microscopic confirmation of pulmonary intraparenchymal nodule or other distant metastasis
AJCC prognostic stage group is assigned based on the stage classification and categories chosen.*
Prognostic stage groups
When T is... And N is... And M is... Then the stage group is...
T1a-T1b N0 M0 I
T2 N0 M0 II
T3 N0 M0 IIIA
T4 N0 M0 IIIB
Any T N1 M0 IVA
Any T N0-N1 M1a IVA
Any T N2 M0-M1a IVB
Any T Any N M1b IVB

AJCC: American Joint Committee on Cancer; TNM: tumor, node, metastasis.

* AJCC data elements required for staging are identified with an asterisk.

Used with permission of the American College of Surgeons, Chicago, Illinois. The original source for this information is the AJCC Cancer Staging System: Thymus, Version 9 (2024).
Graphic 147352 Version 1.0