Incidental finding of a variant in the CFTR gene

CF: cystic fibrosis; CLIA: Clinical Laboratory Improvement Amendments; VUS: variant of uncertain significance.

* Resources for information about variant reclassification include:

• The original testing laboratory
• Curated databases such as ClinVar (https://www.ncbi.nlm.nih.gov/clinvar/)
• A genetic counselor or CF expert