CMC: carpometacarpal; EPL: extensor pollicis longus; IP: interphalangeal; MCP: metacarpophalangeal; RCL: radial collateral ligament; UCL: ulnar collateral ligament.
* If no history of autoimmune disease is known and no systemic symptoms or signs are present, distinguishing between osteoarthritis and rheumatoid arthritis of the thumb early in the course of disease can be difficult. Refer to UpToDate topics discussing thumb pain and specific diseases for further guidance.
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