Algorithm for prediction of peri-procedural bleeding risk in patients undergoing percutaneous coronary intervention

Risk factors*	Integer
Intraaortic balloon pump	5
Age	0 for ≤55 yrs; 3 for every 10 yrs over 55
Female gender	3
Glycoprotein IIb/IIIa inhibitor	3
Baseline HCT <39 percent for men, <36 percent for women	2
LMWH within 48 hr pre-PCI	2
Risk score	Major bleeding (percent)
0	1.0
2 to 6	1.5
7 to 9	2.6
≥10	5.4

eGFR: estimated glomerular filtration rate; HCT: hematocrit; LMWH: low molecular weight heparin.
* The presence of these risk factors leads to assignment of the corresponding integer, which are summated into a score for estimation of risk of peri-procedural bleeding after percutaneous coronary intervention.

Adapted from: Nikolsky E, Mehran R, Dangas G, et al. Development and validation of a prognostic risk score for major bleeding in patients undergoing percutaneous coronary intervention via the femoral approach. Eur Heart J 2007; 2008:1936.

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Algorithm for prediction of peri-procedural bleeding risk in patients undergoing percutaneous coronary intervention