Genotype urine excretion of testosterone

Males who have 2 copies of the gene uridine diphosphoglucuronosyl transferase (ins/ins) have much higher urinary excretion of testosterone glucuronide in the 2 weeks after a single 500 mg dose of testosterone enanthate than those with only a single copy (ins/del) or no copy (del/del). Because the glucuronidation of epitestosterone is not affected by this deletion, the testosterone/epitestosterone ratio also is lower in those with 1 or no copies of the gene than in those with 2 copies.