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خرید پکیج
تعداد آیتم قابل مشاهده باقیمانده : 3 مورد

Frequency of oral clefts in relatives based on the proband's phenotype

Frequency of oral clefts in relatives based on the proband's phenotype
Relative CL (percent) CL/P (percent) CP (percent)
Sibling 2.2 4.6 3.3
Half sibling 0.8 0.7 1.3
Parent 2.5 2.5 2.1
Offspring 3.5 4.1 4.2
Niece/nephew 0.9 0.8 1.1
Aunt/uncle 0.6 1.1 0.6
First cousin 0.3 0.5 0.4
CL: cleft lip; CL/P: cleft lip with or without cleft palate; CP: cleft palate.
Data from: Grosen D, Chavrier C, Skytthe A, et al. A cohort study of recurrence patterns among more than 54,000 relatives of oral cleft cases in Denmark: support for the multifactorial threshold model of inheritance. J Med Genet 2010;47:162.
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