Episodes of sleep apnea in hypothyroid patients, 6 with obesity (red bars) and 3 without obesity (blue bars) before and after 3 to 12 months of thyroxine (T4; levothyroxine) therapy. The frequency of episodes decreased significantly without a change in weight.
Data from: Rajagopal KR, Abbrecht PH, Derderian SS, et al. Obstructive sleep apnea in hypothyroidism. Ann Intern Med 1984; 101:491.
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