TR isoform-specific actions

Thyroid hormone target	Mediating receptor
TSH suppression	TR-beta-2
Bone development	TR-alpha
Neural differentiation	TR-alpha
Cochlear and cone development	TR-beta/TR-beta-2
Cardiac gene expression and heart rate	TR-alpha>TR-beta
Hepatic gene expression	TR-beta>TR-alpha
Catecholamine potentiation	TR-alpha
UCP1 stimulation	TR-beta

TR: thyroid hormone receptor; TSH: thyroid-stimulating hormone; UCP1: uncoupling protein 1.

Graphic 51065 Version 2.0

آیا می خواهید مدیلیب را به صفحه اصلی خود اضافه کنید؟