Nonplatinum-based combination regimens for advanced NSCLC

Regimen	Dose and schedule	Frequency	Reference
Gemcitabine/Docetaxel	Gemcitabine 1000 mg/m2 days 1, 8 Docetaxel 85 mg/m2 day 8	Every 3 weeks	Ann Oncol 2005; 16:602
Gemcitabine/Paclitaxel	Gemcitabine 1000 mg/m2 days 1, 8 Paclitaxel 200 mg/m2 day 1	Every 3 weeks	J Clin Oncol 2002; 20:3578
Paclitaxel/Vinorelbine	Paclitaxel 135 mg/m2 day 1 Vinorelbine 25 mg/m2 day 1	Every 2 weeks	Ann Oncol 2004; 15:1048
Gemcitabine/Vinorelbine	Gemcitabine 1000 mg/m2 days 1, 8 Vinorelbine 25 mg/m2 days 1, 8	Every 3 weeks	J Clin Oncol 2004; 22:2348

Nonplat_combinations_NSCLC.htm

These are representative doses and schedules, which have varied in different trials.

NSCLC: Non-small cell lung cancer.

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