Levels of hematopoietic toxicity following radiation exposure

Degree	ALC	ANC	Platelet count	Bleeding and anemia
0*	1400 to 3500	4000 to 9000	140 to 400,000	None
1	≥1500	≥2000	≥100,000	Petechiae, bruising
				Normal Hb level
2	1000 to 1500	1000 to 2000	50 to 100,000	Mild blood loss
				<10 percent decrease in Hb
3	500 to 1000	500 to 1000	20 to 50,000	Gross blood loss
				10 to 20 percent decrease in Hb
4	<500	<500	<20,000	Spontaneous bleeding
				>20 percent decrease in Hb

ALC: absolute lymphocyte count in cells/microL; ANC: absolute neutrophil count in cells/microL; Platelet count: platelet count in cells/microL; Hb: hemoglobin concentration.
* Degree 0 represents normal reference values.

Modified with permission from: Waselenko JK, MacVittie TJ, Blakely WF, et al. Medical management of the acute radiation syndrome: Recommendations of the strategic national stockpile radiation working group. Ann Intern Med 2004; 140:1037. Copyright © 2004 American College of Physicians.

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Levels of hematopoietic toxicity following radiation exposure