Pericentric inversion of chromosome 7

In a pericentric inversion, the inverted chromosome segment involves part of both chromosome arms and spans the centromere. This patient (GTG stained chromosome on the right) has a pericentric inversion of chromosome 7. The boxed area corresponds to the area between the two red arrows in the normal chromosome 7 (center) and to the indicated bands on the representation of chromosome 17 (left). The black bar to the left of both GTG banded chromosomes shows the location of the centromere. This pericentric inversion changed the position of the centromere.